mRNA synthesis
We can custom synthesize your mRNAs.
Neo Biotech can synthesize mRNAs that mimic fully processed mature mRNAs.
There are 3 categories of mRNAs:
- Reporter gene mRNAs: ideal controls to study transfection efficiency
- Genome editing mRNA: Cas9 mRNA for CRISPR Genome editing
- Vaccine mRNAs: ideal as controls for immunization or vaccine studies
These mRNAs are stabilized with 5' Cap 1 structure and 3' poly(A) tail and are optimized to yield improved stability and performance.
They are modified with 5-methoxyuridine (5moU replaces U) to reduce innate immune responses. We also offer unmodified mRNAs.
We are able to synthesis custom mRNAs at microgram to multigram scales, from a few hundred up to several thousand bases, with a wide variety of modifications.