General Info
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 34pg/mL |
| Detection Limit: | 78.1-5000pg/mL |
| Short Description: | This MPO Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
Information
| Gene Symbol: | Mpo |
| Gene ID: | 17523 |
| Uniprot ID: | PERM_MOUSE |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Description
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low density lipoprotein particles and limits vascular damage. |
| Protein Name | MyeloperoxidaseMpo Cleaved Into - Myeloperoxidase Light Chain - Myeloperoxidase Heavy Chain |
| Database Links | Reactome: R-MMU-6798695Reactome: -MMU-8941413 |
| Cellular Localisation | Lysosome |
| Alternative ELISA Names | Myeloperoxidase ELISA kitMpo Cleaved Into - Myeloperoxidase Light Chain - Myeloperoxidase Heavy Chain ELISA kitMpo ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance