KLHL13 Polyclonal Antibody, PerCP-Cy7 Conjugated
Cat# bs-7752R-PerCP-Cy7
Size : 100ul
Brand : Bioss
KLHL13 Polyclonal Antibody, PerCP-Cy7 Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-7752R-PerCP-Cy7 |
Product Name | KLHL13 Polyclonal Antibody, PerCP-Cy7 Conjugated |
Applications | WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Reactivity | Zebrafish |
Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit |
Specifications | |
Conjugation | PerCP-Cy7 |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human KLHL13 |
Immunogen Range | 351-450/655 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 90293 |
Subcellular location | Cytoplasm |
Synonyms | Kelch-like protein 13; BTB and kelch domain-containing protein 2; KLH13_HUMAN. |
Background | KLHL13 (kelch like 13), also known as BKLHD2 (BTB and kelch domain containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate specific adapter of an E3 ubiquitin protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin mediated proteolysis. Via its BTB and C terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL3 ligase. |
Application Dilution | |
WB | 1:300-5000 |
IF(IHC-P) | 1:50-200 |
IF(IHC-F) | 1:50-200 |
IF(ICC) | 1:50-200 |