Anti-WDR5 antibody (157-174)

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.67 µg/µl
Dilution Range:	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:200 IHC: 1:100
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	WDR5
Gene ID:	11091
Uniprot ID:	WDR5_HUMAN
Immunogen Region:	157-174
Immunogen:	Synthetic peptide: DVKTGKCLKTLPAHSDPV corresponding to amino acids 157-174 of Human WDR5 protein.

Function	Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation. In association with RBBP5 and ASH2L, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.
Protein Name	Wd Repeat-Containing Protein 5 Bmp2-Induced 3-Kb Gene Protein
Database Links	Reactome: R-HSA-3214841 Reactome: R-HSA-3214847 Reactome: R-HSA-3214858 Reactome: R-HSA-5617472 Reactome: R-HSA-8936459 Reactome: R-HSA-8951664 Reactome: R-HSA-9733709 Reactome: R-HSA-9772755
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Wd Repeat-Containing Protein 5 antibody Anti-Bmp2-Induced 3-Kb Gene Protein antibody Anti-WDR5 antibody Anti-BIG3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance