Biotrend USA > Vegfc rabbit polyclonal antibody, Azide Free
Vegfc rabbit polyclonal antibody, Azide Free
Cat# DP3507
Size : 200ug
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Vegfc Rabbit Polyclonal Antibody
| Product Data | |
| Application | ELISA, IP, WB |
|---|---|
| Recommended Dilution | ELISA: 2.5 µg/ml, allows the detection of 0.5-1.0 ng/well of recombinant rat VEGF-C. Western Blot: 2-5 μg/ml. |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Recombinant Rat VEGF-C native protein.(Asp101-Ile221) derived from insect cells (Cat.-No DA3519X) |
| Specificity | The antibody will react with Rat VEGF-C and will cross-react with Human and Mouse VEGF-C proteins. |
| Buffer | PBS, pH 7.4, containing no preservative. State: Azide Free State: Lyophilized purified Ig fraction. |
| Reconstitution Method | Restore in sterile water to a concentration of > 0.5 mg/ml. |
| Purification | Protein A affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for 2 weeks or (in aliquots) at -20°C up to 6 month. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Gene Name | vascular endothelial growth factor C |
| Database Link | |
| Background | VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant, fully processed rat VEGF-C is a 16-18 kDa non-disulfide linked homodimeric protein consisting of two 116 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition. |
| Synonyms | VEGFC, VRP, Vascular endothelial growth factor C, Vascular endothelial growth factor-related protein, Flt4 ligand |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.