Tween 80 [9005-65-6]
Cat# HY-Y1891-50mL
Size : 50mL
Brand : MedChemExpress
Tween 80 (Polysorbate 80), a surfactant, has been widely used as a solvent for pharmacological experiments. Tween 80 can also reduce bacterial attachment and inhibit biofilm formation.
For research use only. We do not sell to patients.
Tween 80 Chemical Structure
CAS No. : 9005-65-6
Based on 53 publication(s) in Google Scholar
Description |
Tween 80 (Polysorbate 80), a surfactant, has been widely used as a solvent for pharmacological experiments. Tween 80 can also reduce bacterial attachment and inhibit biofilm formation. |
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In Vitro |
Tween 80 (Polysorbate 80) is a surfactant which can also reduce bacterial attachment and inhibit biofilm formation[1]. Solubility enhancement as high as 100-fold is achieved using 1% Tween 80 in vitro[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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In Vivo |
Tween 80 (Polysorbate 80) (IP; 10 ml/kg) significantly decreases locomotor activity at a concentration of 32% in saline (v/v) in male outbred (BALB/c x DBA/Z)F1 mice weighing 24-30 g[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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CAS No. |
9005-65-6 |
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Appearance |
Liquid (Density: 1.1 g/cm3) |
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Color |
Colorless to light yellow |
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SMILES |
[Tween 80] |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
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Solvent & Solubility |
In Vitro:
DMSO : ≥ 100 mg/mL H2O : 50 mg/mL (Need ultrasonic) *"≥" means soluble, but saturation unknown.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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Purity & Documentation | |||||||||||||
References |
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Tween 80 Related Classifications
- Others
- Others
- Biochemical Assay Reagents
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
Tween 809005-65-6Polysorbate 80Tween80Tween-80Polysorbate80Polysorbate-80Biochemical Assay ReagentsInhibitorinhibitorinhibit