Sulbactam [68373-14-8]
Cat# HY-B0334-100mg
Size : 100mg
Brand : MedChemExpress
Sulbactam (CP45899) is a competitive, irreversible beta-lactamase inhibitor. Sulbactam shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex.
For research use only. We do not sell to patients.
Sulbactam Chemical Structure
CAS No. : 68373-14-8
This product is a controlled substance and not for sale in your territory.
Based on 7 publication(s) in Google Scholar
Other Forms of Sulbactam:
- Sulbactam sodium In-stock
View All Antibiotic Isoform Specific Products:
Description |
Sulbactam (CP45899) is a competitive, irreversible beta-lactamase inhibitor. Sulbactam shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex[1][2]. |
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IC50 & Target |
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In Vitro |
Sulbactam has a wide range of antibacterial activity that includes Gram-positive and Gram-negative aerobic and anaerobic bacteria[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Clinical Trial |
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Molecular Weight |
233.24 |
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Formula |
C8H11NO5S |
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CAS No. |
68373-14-8 |
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Appearance |
Solid |
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Color |
Light yellow to yellow |
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SMILES |
O=C([C@@H](C(C)(C)S([C@]1(16)C2)(=O)=O)N1C2=O)O |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
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Solvent & Solubility |
In Vitro:
DMSO : ≥ 100 mg/mL (428.74 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) H2O : 20 mg/mL (85.75 mM; Need ultrasonic) *"≥" means soluble, but saturation unknown. Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
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Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
For the following dissolution methods, please prepare the working solution directly.
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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Purity & Documentation |
Purity: 99.75% |
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References |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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H2O / DMSO | 1 mM | 4.2874 mL | 21.4371 mL | 42.8743 mL | 107.1857 mL |
5 mM | 0.8575 mL | 4.2874 mL | 8.5749 mL | 21.4371 mL | |
10 mM | 0.4287 mL | 2.1437 mL | 4.2874 mL | 10.7186 mL | |
15 mM | 0.2858 mL | 1.4291 mL | 2.8583 mL | 7.1457 mL | |
20 mM | 0.2144 mL | 1.0719 mL | 2.1437 mL | 5.3593 mL | |
25 mM | 0.1715 mL | 0.8575 mL | 1.7150 mL | 4.2874 mL | |
30 mM | 0.1429 mL | 0.7146 mL | 1.4291 mL | 3.5729 mL | |
40 mM | 0.1072 mL | 0.5359 mL | 1.0719 mL | 2.6796 mL | |
50 mM | 0.0857 mL | 0.4287 mL | 0.8575 mL | 2.1437 mL | |
60 mM | 0.0715 mL | 0.3573 mL | 0.7146 mL | 1.7864 mL | |
80 mM | 0.0536 mL | 0.2680 mL | 0.5359 mL | 1.3398 mL | |
DMSO | 100 mM | 0.0429 mL | 0.2144 mL | 0.4287 mL | 1.0719 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Sulbactam Related Classifications
- Anti-infection
- Bacterial Antibiotic