Reagents and instruments for immunology, cell biology and molecular biology.
 
> STX-478 is an allosteric PI3Kα inhibitor that selectively targets prevalent PI3Kα helical- and kinase-domain mutant tumors. STX-478 provides robust efficacy while avoiding the metabolic dysfunction associated with the nonselective inhibitor alpelisib. [[2883540-92-7]]

STX-478 is an allosteric PI3Kα inhibitor that selectively targets prevalent PI3Kα helical- and kinase-domain mutant tumors. STX-478 provides robust efficacy while avoiding the metabolic dysfunction associated with the nonselective inhibitor alpelisib. [[2883540-92-7]]

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Cat# orb1910725-100mg

Size : 100mg

Brand : Biorbyt


    STX-478

    STX-478

    Catalog Number: orb1910725

    Catalog Numberorb1910725
    CategorySmall Molecules
    DescriptionSTX-478 is an allosteric PI3Kα inhibitor that selectively targets prevalent PI3Kα helical- and kinase-domain mutant tumors. STX-478 provides robust efficacy while avoiding the metabolic dysfunction associated with the nonselective inhibitor alpelisib.
    CAS Number[2883540-92-7]
    MW401.297
    SMILESNC1=NC=C(C=N1)NC(N[C@H](C2=C(C3=CC(F)=CC(F)=C3O2)C)C(F)(F)F)=O
    FormulaC16H12F5N5O2
    NoteFor research use only
    Expiration Date12 months from date of receipt.