STX-478 is an allosteric PI3Kα inhibitor that selectively targets prevalent PI3Kα helical- and kinase-domain mutant tumors. STX-478 provides robust efficacy while avoiding the metabolic dysfunction associated with the nonselective inhibitor alpelisib. [[2883540-92-7]]
Cat# orb1910725-1g
Size : 1g
Brand : Biorbyt
STX-478
Catalog Number: orb1910725
Catalog Number | orb1910725 |
---|---|
Category | Small Molecules |
Description | STX-478 is an allosteric PI3Kα inhibitor that selectively targets prevalent PI3Kα helical- and kinase-domain mutant tumors. STX-478 provides robust efficacy while avoiding the metabolic dysfunction associated with the nonselective inhibitor alpelisib. |
CAS Number | [2883540-92-7] |
MW | 401.297 |
SMILES | NC1=NC=C(C=N1)NC(N[C@H](C2=C(C3=CC(F)=CC(F)=C3O2)C)C(F)(F)F)=O |
Formula | C16H12F5N5O2 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |