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Flow Cytometry
Flow cytometric analysis of K562 cells with STAT4 (phospho Y693) monoclonal antibody, clone F6 (PE) (Cat # MAB19137). Unstained imatinib treated cells as negative control (blue) or stained and treated with imatinib (red) or treated with IFNa + IL-4 + pervanadate (green).
- Specifications
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human STAT4.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Y693 of human STAT4.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Conjugation
PE
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Flow Cytometry
Flow cytometric analysis of K562 cells with STAT4 (phospho Y693) monoclonal antibody, clone F6 (PE) (Cat # MAB19137). Unstained imatinib treated cells as negative control (blue) or stained and treated with imatinib (red) or treated with IFNa + IL-4 + pervanadate (green). - Gene Info — STAT4
Entrez GeneID
6775Gene Name
STAT4
Gene Alias
SLEB11
Gene Description
signal transducer and activator of transcription 4
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. [provided by RefSeq
Other Designations
OTTHUMP00000163553
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