General Info
Applications: | ELISA |
Reactivity: | Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 2.19pg/mL |
Detection Limit: | 7.81-500pg/mL |
Short Description: | This EDN1 Competitive ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 2.5 hrs |
Information
Gene Symbol: | Edn1 |
Gene ID: | 24323 |
Uniprot ID: | EDN1_RAT |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Description
Tissue Specificity | |
Post Translational Modifications | |
Function | Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. Also binds the DEAR/FBXW7-AS1 receptor. |
Protein Name | Endothelin-1Et-1Preproendothelin-1Ppet1 Cleaved Into - Big Endothelin-1 |
Database Links | Reactome: R-RNO-375276Reactome: -RNO-416476 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Endothelin-1 ELISA kitEt-1 ELISA kitPreproendothelin-1 ELISA kitPpet1 Cleaved Into - Big Endothelin-1 ELISA kitEdn1 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance