- More Files
Western Blot (Tissue lysate)
PRDX6 monoclonal antibody (M01), clone 3A10-2A11. Western Blot analysis of PRDX6 expression in human liver.
Western Blot (Cell lysate)
PRDX6 monoclonal antibody (M01), clone S1. Western Blot analysis of PRDX6 expression in MCF-7.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PRDX6 is 3 ng/ml as a capture antibody.
Western Blot detection against Immunogen (50.38 KDa) .
- Specifications
Product Description
Mouse monoclonal antibody raised against a full length recombinant PRDX6.
Immunogen
PRDX6 (AAH35857.1, 1 a.a. ~ 224 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MPGGLLLGDVAPNFEANTTVGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGMLDPAEKDEKGMPVTARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVDWKDGDSVMVLPTIPEEEAKKLFPKGVFTKELPSGKKYLRYTPQP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (91)
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (50.38 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Applications
Western Blot (Tissue lysate)
PRDX6 monoclonal antibody (M01), clone 3A10-2A11. Western Blot analysis of PRDX6 expression in human liver.Western Blot (Cell lysate)
PRDX6 monoclonal antibody (M01), clone S1. Western Blot analysis of PRDX6 expression in MCF-7.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PRDX6 is 3 ng/ml as a capture antibody.ELISA
- Gene Info — PRDX6
Entrez GeneID
9588GeneBank Accession#
BC035857Protein Accession#
AAH35857.1Gene Name
PRDX6
Gene Alias
1-Cys, AOP2, KIAA0106, MGC46173, NSGPx, PRX, aiPLA2, p29
Gene Description
peroxiredoxin 6
Omim ID
602316Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq
Other Designations
1-Cys peroxiredoxin|OTTHUMP00000032693|acidic calcium-independent phospholipase A2|antioxidant protein 2|non-selenium glutathione peroxidase
- Interactomes
- Pathways
- Diseases
- Publication Reference
- Relationships between the abundance of 29 proteins and several meat or carcass quality traits in two bovine muscles revealed by a combination of univariate and multivariate analyses.
Brigitte Picard, Arnaud Cougoul, Sébastien Couvreur, Muriel Bonnet.
Journal of Proteomics 2022 Dec; 273:104792.
Application：Array, Bovine, Bovine muscles.
- Protein Array-Based Approach to Evaluate Biomarkers of Beef Tenderness and Marbling in Cows: Understanding of the Underlying Mechanisms and Prediction.
Mohammed Gagaoua, Muriel Bonnet, Brigitte Picard.
Foods (Basel, Switzerland) 2020 Aug; 9(9):E1180.
Application：Reverse Phase Protein Array (RPPA), Human, Human muscle protein.
- Quantification of biomarkers for beef meat qualities using a combination of Parallel Reaction Monitoring- and antibody-based proteomics.
Muriel Bonnet, Julien Soulat, Joanna Bons, Stéphanie Léger, Leanne De Koning, Christine Carapito, Brigitte Picard.
Food Chemistry 2020 Jul; 317:126376.
Application：Array, Bovine, Bovine longissimus thoracis, Bovine semimembranosus.
- Beef tenderness and intramuscular fat proteomic biomarkers: Effect of gender and rearing practices.
Picard B, Gagaoua M, Al Jammas M, Bonnet M.
Journal of Proteomics 2019 Mar; 200:1.
Application：WB-Ti, Bovine, Bovine muscle.
- Global analysis of erythroid cells redox status reveals the involvement of Prdx1 and Prdx2 in the severity of beta thalassemia.
Romanello KS, Teixeira KKL, Silva JPMO, Nagamatsu ST, Bezerra MAC, Domingos IF, Martins DAP, Araujo AS, Lanaro C, Breyer CA, Ferreira RA, Franco-Penteado C, Costa FF, Malavazi I, Netto LES, de Oliveira MA, Cunha AF.
PLoS One 2018 Dec; 13(12):e0208316.
Application：WB, Human, Erythrocytes of patients with β-thalassemia.
- Reverse Phase Protein array for the quantification and validation of protein biomarkers of beef qualities: The case of meat color from Charolais breed.
Gagaoua M, Bonnet M, De Koning L, Picard B.
Meat Science 2018 Jul; 145:308.
Application：WB-Ti, Bovine, Bovine muscle.
- Beef tenderness and intramuscular fat proteomic biomarkers: muscle type effect.
Picard B, Gagaoua M, Al-Jammas M, De Koning L, Valais A, Bonnet M.
PeerJ 2018 Jun; 6:e4891.
Application：WB-Ti, Bovine, Bovine muscle.
- Reverse phase protein arrays for the identification/validation of biomarkers of beef texture and their use for early classification of carcasses.
Gagaoua M, Bonnet M, Ellies-Oury MP, De Koning L, Picard B.
Food Chemistry 2018 Jun; 250:245.
Application：WB-Ti, Bovine, Bovine muscles.
- The study of protein biomarkers to understand the biochemical processes underlying beef color development in young bulls.
Gagaoua M, Terlouw EMC, Picard B.
Meat Science 2017 Jul; 134:18.
Application：Dot, Bovine, Bovine muscle.
- Inverse relationships between biomarkers and beef tenderness according to contractile and metabolic properties of the muscle.
Picard B, Gagaoua M, Micol D, Cassar-Malek I, Hocquette JF, Terlouw CE.
Journal of Agricultural and Food Chemistry 2014 Oct; 62(40):9808.
Application：Dot, Bovine, Bovine muscle.
- Cellular and molecular large-scale features of fetal adipose tissue: is bovine perirenal adipose tissue brown?.
Taga H, Chilliard Y, Meunier B, Chambon C, Picard B, Zingaretti MC, Cinti S, Bonnet M.
Journal of Cellular Physiology 2012 Apr; 227(4):1688.
Application：WB-Ti, Bovine, Adipose tissue.
- Functional analysis of beef tenderness.
Guillemin N, Bonnet M, Jurie C, Picard B.
Journal of Proteomics 2011 Dec; 75(2):352.
Application：WB-Ti, Bovine, Bovine tenderness.
- Peroxiredoxin-6?XA potential protein marker for meat tenderness in bovine longissimus thoracis muscle.
Jia X, Veiseth-Kent E, Grove H, Kuziora P, Aass L, Hildrum KI, Hollung K.
Journal of Animal Science 2009 Jul; 87(7):2391.
Application：WB, Bovine, Bovine M. longissimus thoracis biopsies.
- Relationships between the abundance of 29 proteins and several meat or carcass quality traits in two bovine muscles revealed by a combination of univariate and multivariate analyses.