PNPO Human shRNA Plasmid Kit (Locus ID 55163)

Cat# TR302389

Size : 1kit


PNPO Human shRNA Plasmid Kit (Locus ID 55163)

SKU
TR302389
PNPO - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
In Stock*
Specifications
Product Data
Locus ID 55163
Synonyms HEL-S-302; PDXPO
Vector pRS
E. coli Selection Ampicillin
Format Retroviral plasmids
Components PNPO - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 55163). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_018129, NM_018129.1, NM_018129.2, NM_018129.3, BC006525, BC006525.2, NM_018129.4
UniProt ID Q9NVS9
Summary The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq, Oct 2008]
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@biotrend-usa.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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