PEI Transfection Reagent
Cat# HY-K2014-10mL
Size : 10mL
Brand : MedChemExpress
MCE PEI Transfection Reagent is designed based on 25 kDa PEI. It has high-efficiency, low-toxicity, strong-stability, and is suitable for many cell types, such as HEK-293、HEK-293T、CHO-K1、COS-1、COS-7、NIH/3T3、Sf9、HepG2 and HeLa et, even some hard-to-transfect cells. It can also be applied to large-scale recombinant protein expression and virus production.
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11 Publications Citing Use of MCE PEI Transfection Reagent
- •J Extracell Vesicles. 2024 Nov;13(11):e70012. [Abstract]
- •Int J Biol Macromol. 2023 Oct 15;253(Pt 7):127344. [Abstract]
- •Phytother Res. 2024 Jul 11. [Abstract]
- •Biochim Biophys Acta Mol Basis Dis. 2024 Apr 22;1870(5):167183. [Abstract]
- •Cell Biosci. 2023 Jul 10;13(1):128. [Abstract]
- •Transl Oncol. 2024 Aug 24:49:102081. [Abstract]
- •Int J Mol Sci. 2023 Dec 28, 25(1), 424.
- •Exp Cell Res. 2024 May 13:114068. [Abstract]
- •SSRN. 2024 Oct 15.
- •bioRxiv. 2024 August 06.
- •bioRxiv. 2024 July 12.
| Description & Advantages |
PEI is a commonly used polymer carrier in gene transfection. It consists of cationic polymers and can introduce nucleic acids into eukaryotic cells. In polymer-based transfection, exogenous DNA forms complexes with cationic polymers that enter host cells by endocytosis. MCE PEI Transfection Reagent is designed based on 25 kDa PEI. It is modified by introducing functional genes to enhance the binding ability of DNA, and reduced the cytotoxicity. In addition, the cell uptake and the endosome escape functions of PEI modified was enhanced significantly. MCE PEI Transfection Reagent is high-efficiency, low-toxicity, strong-stability, and suitable for many cell types, such as HEK-293、HEK-293T、CHO-K1、COS-1、COS-7、NIH/3T3、Sf9、HepG2 and HeLa et, even some hard-to-transfect cells. It can also be applied to large-scale recombinant protein expression and virus production. |
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| Storage |
-20°C, 1 year. Avoid repetitive freeze-thaw cycles. |
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| Components |
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| Documentation |
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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
