MUC5AC (Apomucin Major Airway GlycoProtein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin, TBM, Mucin 5AC, Gastric Mucin)
Cat# 138572-AF-100ug
Size : 100ug
Brand : US Biological
138572-AF Rabbit Anti-MUC5AC (Apomucin Major Airway GlycoProtein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin, TBM, Mucin 5AC, Gastric Mucin)
Clone Type
PolyclonalHost
mouseSource
humanSwiss Prot
P98088Isotype
IgG1,kApplications
E IHCCrossreactivity
Ch Fe Hu Mk Mo Po Rb RtAccession #
XP_003403498Shipping Temp
Blue IceStorage Temp
-20°CThis monoclonal antibody recognizes the peptide core of gastric mucin M1 (>1,000kD) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epi thelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not w ith normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin r eactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fet al colonic) mucins.||Applications:|Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.||Recommended Dilution:|Immunohistochemistry (Formalin-fixed): Staining of formalin-fixed tissue requires boiling tissue sections in 10mM citrate buffer, pH 6, for 10-20mins followed by coooling at RT for 20mins.|Optimal dilutions to be determined by the researcher.||Positive Control:|Stomach||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.