General Info
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.063ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This DSTYK Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
Information
| Gene Symbol: | Dstyk |
| Gene ID: | 213452 |
| Uniprot ID: | DUSTY_MOUSE |
| Sample Type: | tissue homogenates or other biological fluids. |
Description
| Tissue Specificity | Expressed in brain, heart, skeletal muscle, kidney and lung. Expressed in maturing tubular epithelia, with the most prominent expression in the medulla and the papilla. Expressed in thin ascending limb of the loop of Henle and the distal convoluted tubule. Expressed in all layers of transitional ureteric epithelium and in the ureteric smooth-muscle cells (at protein level). Widely expressed. Highly expressed in many brain regions, including in cerebellum, olfactory, hippocampus and cerebral cortex. |
| Post Translational Modifications | |
| Function | Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types. |
| Protein Name | Dual Serine/Threonine And Tyrosine Protein KinaseDusty Protein KinaseDusty PkReceptor-Interacting Serine/Threonine-Protein Kinase 5 |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembraneApical Cell MembraneBasolateral Cell MembraneCell JunctionDetected In Basolateral And Apical Membranes Of All Tubular EpitheliaDetected At Apical Cell-Cell JunctionsColocalized With Fgf Receptors To The Cell Membrane |
| Alternative ELISA Names | Dual Serine/Threonine And Tyrosine Protein Kinase ELISA kitDusty Protein Kinase ELISA kitDusty Pk ELISA kitReceptor-Interacting Serine/Threonine-Protein Kinase 5 ELISA kitDstyk ELISA kitRipk5 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance