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- Specifications
Product Description
MID1 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of MID1 expression in cultured cells.
Suitable Sample
Attached Cell, Loosely Attached Cell, Suspension Cell.
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human, Mouse, Rat
Regulatory Status
For research use only (RUO)
Storage Instruction
Store at 4°C for six months.
- Applications
Qualitative
- Gene Info — MID1
Entrez GeneID
4281Protein Accession#
O15344Gene Name
MID1
Gene Alias
BBBG1, FXY, GBBB1, MIDIN, OGS1, OS, OSX, RNF59, TRIM18, XPRF, ZNFXY
Gene Description
midline 1 (Opitz/BBB syndrome)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Several different transcript variants are generated by alternate splicing; however, the full-length nature of some of the variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000022896|OTTHUMP00000022898|OTTHUMP00000022900|OTTHUMP00000022901|midline 1|midline 1 ring finger|putative transcription factor XPRF|tripartite motif protein TRIM18|zinc finger on X and Y, mouse, homolog of
- Interactomes
- Pathways
- Diseases