Reagents and instruments for immunology, cell biology and molecular biology.

Lsk Monoclonal Antibody

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Cat# BT-MCA0853-50ul

Size : 50ul

Brand : Bioassay Technology Laboratory

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Lsk Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, FCM, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, FCM, ELISA

Product overview

Full product name

Megakaryocyte-associated tyrosine-protein kinase

Code

BT-MCA0853

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human Lsk expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Antibody are purified by protein G affinity chromatography. Liquid in PBS containing 50% glycerol and 0.03% sodium azide.

Storage

-20°C for one year

Background

The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Uniprot accession

Human:;Mouse:;

Molecular weight

N/A

Gene ID

Human: 4145

Synonyms

MATK; CTK; HYL; Megakaryocyte-associated tyrosine-protein kinase; CSK homologous kinase; CHK; Hematopoietic consensus tyrosine-lacking kinase; Protein kinase HYL; Tyrosine-protein kinase CTK

Research area

Signal transduction; Immunology

Target protein

MATK

Recommended dilution

Application	Dilution
ELISA	1:10000
FC	1:200 - 1:400
WB	1:500 - 1:2000

Images

Western Blot analysis using Lsk Monoclonal antibody against K562 cell lysate (1).

Flow cytometric analysis of K562 cells using Lsk Monoclonal antibody (green) and negative control (purple).

Protocols

> Protocol Booklet

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