The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
- Specifications
Product Description
LEP (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human leptin in serum, plasma.
Suitable Sample
Plasma (Citrate, EDTA, Heparin), Serum
Sample Volume
100 uL
Label
HRP-conjugate
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
1 to 50 ng/mL
Limit of Detection
0.2 ng/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store the kit at 4°C.
- Applications
Quantification
- Gene Info — LEP
Entrez GeneID
3952Gene Name
LEP
Gene Alias
FLJ94114, OB, OBS
Gene Description
leptin
Omim ID
164160Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq
Other Designations
leptin (murine obesity homolog)|leptin (obesity homolog, mouse)|obese, mouse, homolog of|obesity factor
- Interactomes
- Pathways
- Diseases
- Publication Reference
- Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia.
Nandor Gabor Than, Roberto Romero, Adi Laurentiu Tarca, Katalin Adrienna Kekesi, Yi Xu, Zhonghui Xu, Kata Juhasz, Gaurav Bhatti, Ron Joshua Leavitt, Zsolt Gelencser, Janos Palhalmi, Tzu Hung Chung, Balazs Andras Gyorffy, Laszlo Orosz, Amanda Demeter, Anett Szecsi, Eva Hunyadi-Gulyas, Zsuzsanna Darula, Attila Simor, Katalin Eder, Szilvia Szabo, Vanessa Topping, Haidy El-Azzamy, Christopher LaJeunesse, Andrea Balogh, Gabor Szalai, Susan Land, Olga Torok, Zhong Dong, Ilona Kovalszky, Andras Falus,
Frontiers in Immunology 2018 Aug; 9:1661.
Application：Quant, Human, Human plasma.
- N-Acetylcysteine improves oocyte and embryo quality in polycystic ovary syndrome patients undergoing intracytoplasmic sperm injection: an alternative to metformin.
Cheraghi E, Mehranjani MS, Shariatzadeh MA, Esfahani MH, Ebrahimi Z.
Reproduction, Fertility, and Development 2016 Apr; 28(6):723.
Application：ELISA, Human, Follicular fluid.
- Co-Administration of Metformin and N-Acetyl Cysteine Fails to Improve Clinical Manifestations in PCOS Individual Undergoing ICSI.
Cheraghi E, Soleimani Mehranjani M, Shariatzadeh MA, Nasr Esfahani MH, Ebrahimi Z.
International Journal of Fertility & Sterility 2014 Jul; 8(2):119.
Application：S-ELISA, Human, Serum.
- Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia.