Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: KDR-hIgGFc transfected HEK293 cell lysates with KDR monoclonal antibody, clone 1A9A3 (Cat # MAB21485).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with KDR monoclonal antibody, clone 1A9A3 (Cat # MAB21485).
Flow Cytometry
Flow cytometric analysis of HeLa cells with KDR monoclonal antibody, clone 1A9A3 (Cat # MAB21485) (Green). Red: Negative Control.
- Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant human KDR.
Immunogen
Recombinant protein corresponding to amino acids 1225-1356 of human KDR.
Host
Mouse
Theoretical MW (kDa)
151.5
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: KDR-hIgGFc transfected HEK293 cell lysates with KDR monoclonal antibody, clone 1A9A3 (Cat # MAB21485).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with KDR monoclonal antibody, clone 1A9A3 (Cat # MAB21485).Flow Cytometry
Flow cytometric analysis of HeLa cells with KDR monoclonal antibody, clone 1A9A3 (Cat # MAB21485) (Green). Red: Negative Control. - Gene Info — KDR
Entrez GeneID
3791Protein Accession#
P35968Gene Name
KDR
Gene Alias
CD309, FLK1, VEGFR, VEGFR2
Gene Description
kinase insert domain receptor (a type III receptor tyrosine kinase)
Gene Ontology
HyperlinkGene Summary
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq
Other Designations
soluble VEGFR2|vascular endothelial growth factor receptor 2
- Interactomes
- Pathways
- Diseases
- Adenocarcinoma
- Alzheimer disease
- Angina Pectoris
- Anoxia
- Asthma
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
+ View More Disease