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- Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant rat Kcnj8.
Immunogen
Recombinant protein corresponding to amino acids 306-424 at C-terminus of rat Kcnj8.
Host
Mouse
Reactivity
Rat
Form
Liquid
Conjugation
APC
Purification
Protein G purification
Isotype
IgG2a
Recommend Usage
Immunocytochemistry (1:100)
Immunofluorescence (1:100)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide).
Storage Instruction
Store at -20°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Western Blot (Tissue lysate)
Western Blot analysis of rat brain with Kcnj8 monoclonal antibody, clone S366-60 (APC) (Cat # MAB17359).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
Immunocytochemical staining of SK-N-BE with Kcnj8 monoclonal antibody, clone S366-60 (APC) (Cat # MAB17359). (A) DAPI (blue) nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) Kcnj8 Antibody. (D) Composite.Immunofluorescence
- Gene Info — Kcnj8
Entrez GeneID
25472Protein Accession#
Q63664Gene Name
Kcnj8
Gene Alias
Kir6.1, UKATP1, uKATP-1
Gene Description
potassium inwardly-rectifying channel, subfamily J, member 8
Gene Ontology
HyperlinkGene Summary
subfamily J
Other Designations
Inwardly rectifying potassium channel gene subfamily J-8 (ATP sensitive)|Inwardly rectifying potassium channel gene, subfamily J-8 (ATP sensitive)
- Publication Reference
- Heterogeneity of IK1 in the mouse heart.
Panama BK, McLerie M, Lopatin AN.
American Journal of Hysiology. Heart and Circulatory Physiology 2007 Dec; 293(6):H3558.
- Kir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/Kir2.3 channels in HEK293 cells.
Munoz V, Vaidyanathan R, Tolkacheva EG, Dhamoon AS, Taffet SM, Anumonwo JM.
Heart Rhythm 2007 Apr; 4(4):487.
- Molecular dissection of the inward rectifier potassium current (IK1) in rabbit cardiomyocytes: evidence for heteromeric co-assembly of Kir2.1 and Kir2.2.
Zobel C, Cho HC, Nguyen TT, Pekhletski R, Diaz RJ, Wilson GJ, Backx PH.
The Journal of Physiology 2003 Jul; 550(Pt 2):365.
- Toward understanding the assembly and structure of KATP channels.
Aguilar-Bryan L, Clement JP 4th, Gonzalez G, Kunjilwar K, Babenko A, Bryan J.
Physiological Reviews 1998 Jan; 78(1):227.
- Heterogeneity of IK1 in the mouse heart.