- More Files
- Specifications
Product Description
Mouse monoclonal antibody raised against a full length recombinant IL13.
Immunogen
IL13 recombinant protein.
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.32 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to IL13 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]ELISA
- Gene Info — IL13
Entrez GeneID
3596Gene Name
IL13
Gene Alias
ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600
Gene Description
interleukin 13
Gene Ontology
HyperlinkGene Summary
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq
Other Designations
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- Interactomes
- Pathways
- Diseases
- Publication Reference
- Interleukin 13-positive mast cells are increased in immunoglobulin G4-related sialadenitis.
Takeuchi M, Ohno K, Takata K, Gion Y, Tachibana T, Orita Y, Yoshino T, Sato Y.
Scientific Reports 2015 Jan; 5:7696.
Application:IF, IHC-P, Human, Submandibular glands.
- Interleukin 13-positive mast cells are increased in immunoglobulin G4-related sialadenitis.