Flow Cytometry
FACS analysis of negative control 293 cells (Black) and HFE expressing 293 cells (Green) using HFE purified MaxPab mouse polyclonal antibody.
Western Blot (Cell lysate)
HFE MaxPab polyclonal antibody. Western Blot analysis of HFE expression in HepG2.
Western Blot (Transfected lysate)
Western Blot analysis of HFE expression in transfected 293T cell line (H00003077-T01) by HFE MaxPab polyclonal antibody.
Lane 1: HFE transfected lysate(38.28 KDa).
Lane 2: Non-transfected lysate.
- Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human HFE protein.
Immunogen
HFE (NP_000401.1, 1 a.a. ~ 348 a.a) full-length human protein.
Sequence
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69); Rat (70)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Applications
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and HFE expressing 293 cells (Green) using HFE purified MaxPab mouse polyclonal antibody.Western Blot (Cell lysate)
HFE MaxPab polyclonal antibody. Western Blot analysis of HFE expression in HepG2.Western Blot (Transfected lysate)
Western Blot analysis of HFE expression in transfected 293T cell line (H00003077-T01) by HFE MaxPab polyclonal antibody.
Lane 1: HFE transfected lysate(38.28 KDa).
Lane 2: Non-transfected lysate.
- Gene Info — HFE
Entrez GeneID
3077GeneBank Accession#
NM_000410.3Protein Accession#
NP_000401.1Gene Name
HFE
Gene Alias
HFE1, HH, HLA-H, MGC103790, dJ221C16.10.1
Gene Description
hemochromatosis
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq
Other Designations
MHC class I-like protein HFE|hemochromatosis protein|hereditary hemochromatosis protein HLA-H
- Interactomes
- Diseases