Reagents and instruments for immunology, cell biology and molecular biology.
 
> HDAC-IN-57 is an orally active inhibitor of histone deacetylases (HDAC), with IC50s of 2.07 nM, 4.71 nM, 2.4 nM and 107 nM for HDAC1, HDAC2, HDAC6, HDAC8, respectively. HDAC-IN-57 can inhibits LSD1, with IC50 of 1.34 μΜ. HDAC-IN-57 induces apoptosis, and has anti-tumor activity[1]. [[2716217-79-5]]

HDAC-IN-57 is an orally active inhibitor of histone deacetylases (HDAC), with IC50s of 2.07 nM, 4.71 nM, 2.4 nM and 107 nM for HDAC1, HDAC2, HDAC6, HDAC8, respectively. HDAC-IN-57 can inhibits LSD1, with IC50 of 1.34 μΜ. HDAC-IN-57 induces apoptosis, and has anti-tumor activity[1]. [[2716217-79-5]]

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Cat# orb1910516-1g

Size : 1g

Brand : Biorbyt


    HDAC-IN-57

    HDAC-IN-57

    Catalog Number: orb1910516

    Catalog Numberorb1910516
    CategorySmall Molecules
    DescriptionHDAC-IN-57 is an orally active inhibitor of histone deacetylases (HDAC), with IC50s of 2.07 nM, 4.71 nM, 2.4 nM and 107 nM for HDAC1, HDAC2, HDAC6, HDAC8, respectively. HDAC-IN-57 can inhibits LSD1, with IC50 of 1.34 μΜ. HDAC-IN-57 induces apoptosis, and has anti-tumor activity[1].
    CAS Number[2716217-79-5]
    MW377.4
    SMILESCOC1=CC=C(C2=NC=CC(C(NCC3=CC=C(C(NO)=O)C=C3)=O)=C2)C=C1
    FormulaC21H19N3O4
    NoteFor research use only
    Expiration Date12 months from date of receipt.