Empire Genomics' DNMT3A break apart probe is designed to detect DNMT3A translocations. The probe comes labeled in green and orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
Gene Summary
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]
Gene Details
Gene Symbol: DNMT3A
Gene Name: DNA Methyltransferase 3 Alpha
Chromosome: CHR2: 25455844-25565459
Locus: 2p23.3