Dexamethasone [50-02-2]
Cat# HY-14648-5g
Size : 5g
Brand : MedChemExpress
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist, apoptosis inducer, and common disease inducer in experimental animals, constructing models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has potential for use in COVID-19 research.
For research use only. We do not sell to patients.
Dexamethasone Chemical Structure
CAS No. : 50-02-2
This product is a controlled substance and not for sale in your territory.
Based on 157 publication(s) in Google Scholar
Other Forms of Dexamethasone:
- Dexamethasone acetate In-stock
- Dexamethasone-d5 In-stock
- Dexamethasone-4,6α,21,21-d4 In-stock
- Dexamethasone-d3-1 In-stock
- Dexamethasone phosphate disodium In-stock
- Dexamethasone (GMP) Get quote
- Dexamethasone (Standard) Get quote
- Dexamethasone-d5-1 Get quote
- Dexamethasone-d4 Get quote
- Dexamethasone phosphate Get quote
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Carbohydr Polym. 1 January 2023, 120179.
- Immunofluorescence analysis of Itgb2 in Dexamethasone (100 nM; for 1 hour)-treated MODE-K cells.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Carbohydr Polym. 1 January 2023, 120179.
- mRNA levels of Itgb2 in Dexamethasone (100 nM; for 1 hour)-treated MODE-K cells.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Carbohydr Polym. 1 January 2023, 120179.
- Western blotting analysis of Itgb2 levels in Dexamethasone (100 nM; for 1 hour)-treated MODE-K cells.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: J Cachexia Sarcopenia Muscle. 2022 Aug;13(4):2017-2030. [Abstract]
- qRT‐PCR results show that DEX (DEX; 25 μg/g ; once a day; for 10 days)-induced myotube atrophy can increase the expression levels of MuRF1, Atrogin‐1, FoxO3a, SYISL, and miR‐205‐5p, decrease the expression levels of miR‐23a‐3p and miR‐103‐3p, but does not affect the expression level of SYNPO2.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: J Cachexia Sarcopenia Muscle. 2022 Aug;13(4):2017-2030. [Abstract]
- Western blotting results show that SYISL overexpression can further promote protein ubiquitination levels in Dexamethasone (DEX; 25 μg/g ; once a day; for 10 days)-induced muscular atrophy. Muscle atrophy is induced by intraperitoneal injection of DEX for 10 days in 3‐month‐old wild‐type and KO mice, respectively.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: J Cachexia Sarcopenia Muscle. 2022 Aug;13(4):2017-2030. [Abstract]
- Representative photographs of H&E and Lamin immunofluorescence staining for WT and KO TA muscles. Quantification of five independent experiments shows that knockout of SYISL alleviates muscle weight loss caused by Dexamethasone (DEX; 25 μg/g ; once a day; for 10 days)-induced muscle atrophy.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Oncogene. 2021 Sep;40(35):5367-5378. [Abstract]
- 4T1 cells are treated with Dexamethasone (Dex; 100 nM)/GSK650394 in vitro for 48 h before inoculation via intravenous injection.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Oncogene. 2021 Sep;40(35):5367-5378. [Abstract]
- For in situ treatment in the 4T1 tumor model, Dexamethasone (Dex; 3 mg/kg) is performed every three days by gavage twice/day. The expression of Nedd4l, p-Nedd4l, Smad2 and p-Smad2 after SGK1 knockout.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Oncogene. 2021 Sep;40(35):5367-5378. [Abstract]
- The GR expression of 4T1 cells treated with Dexamethasone (100 nM)/Mifepristone for 48 h.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Oncogene. 2021 Sep;40(35):5367-5378. [Abstract]
- The migration assay of 4T1 cells in different condition. 4T1 cells were pretreated with 100 nM Dexamethasone (Dex) for 48 h and then are used for Transwell.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Br J Pharmacol. 2021 Aug;178(15):2976-2997. [Abstract]
- Primary microglial cells incubated with Protopanaxadiol (100 μM), Dexamethasone (100 nM) or Dexamethasone-BSA (10 nM) show remarkable dynorphin A expression. Pretreatment with Dexamethasone-21-mesylate for 0.5 h completely abolished Protopanaxadiol-, Dexamethasone- or Dexamethasone-BSA-stimulated dynorphin A expression.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Biomaterials. 2020 Feb;232:119730. [Abstract]
- Raw264.7 cells are treated with various concentrations of blank NPs, free Dexamethasone (Dex), Dex/Oxi-αCD NPs, or Dex/FA-Oxi-αCD NPs for 24 h, the optical density values at 450 nm were measured and the cell viability was determined by CCK-8 assay.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Biomaterials. 2020 Feb;232:119730. [Abstract]
- Raw264.7 cells are treated with various concentrations of blank NPs, free Dexamethasone (Dex), Dex/Oxi-αCD NPs, or Dex/FA-Oxi-αCD NPs for 24 h, mRNA level of iRhom2 in Raw264.7 cells is detected by quantitative real-time PCR. Data are presented by the relative amount of mRNA normalized by GAPDH.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Biomaterials. 2020 Feb;232:119730. [Abstract]
- Raw264.7 macrophages induced with LPS (1 μg/mL) for 6 h. Then cellular uptake of Cy5-labeled Dexamethasone (Dex)/OxiαCD NPs or Dex/FA-Oxi-αCD NPs is assessed using confocal laser scanning microscopy at various times.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Biomaterials. 2020 Feb;232:119730. [Abstract]
- Western blot analysis of iRhom2, TNF-α, and BAFF expression in Raw264.7 cells treated with various concentrations of blank NPs, free Dexamethasone (Dex), Dex/Oxi-αCD NPs, or Dex/FA-Oxi-αCD NPs for 24 h.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2020 Oct;180:114145. [Abstract]
- Translocation of FoxO3 after treatment with S-Rg3 in DEX-treated C2C12 myotubes was investigated by immunofluorescence staining.
-
Dexamethasone purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2020 Oct;180:114145. [Abstract]
- After C2C12 myotubes are incubated with Dexamethasone (DEX) and S-Rg3 for 24 h, myotube levels of MuRF1 and atrogin-1 are detected using Western blot analysis.