CY7-SE [477908-53-5]
Cat# HY-D0824-5mg
Size : 5mg
Brand : MedChemExpress
CY7-SE is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance.
For research use only. We do not sell to patients.
CY7-SE Chemical Structure
CAS No. : 477908-53-5
This product is a controlled substance and not for sale in your territory.
Other In-stock Forms of CY7-SE:
-
CY7-SE purchased from MedChemExpress. Usage Cited in: Nano Today. 47 (2022) 101675
- Bio-distribution of the Cy7 SE-labeled PFD Liposome at indicated time points after tail vein injection. Tumors and major organs are dissected, and fluorescence intensities in the major drug metabolizing organs are quantified.
Description |
CY7-SE is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[2]. |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
In Vitro |
Protocol MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||
Molecular Weight |
779.92 |
||||||||||||
Formula |
C39H45N3O10S2 |
||||||||||||
CAS No. |
477908-53-5 |
||||||||||||
Appearance |
Solid |
||||||||||||
Color |
Light brown to black |
||||||||||||
Emission (Em) |
770 |
||||||||||||
Excitation (Ex) |
740 |
||||||||||||
SMILES |
CC(/C(N1CCCCCC(ON2C(CCC2=O)=O)=O)=C\C=C\C=C\C=C\C3=[N+](CC)C(C=CC(S(=O)([O-])=O)=C4)=C4C3(C)C)(C)C5=C1C=CC(S(=O)(O)=O)=C5 |
||||||||||||
Shipping | Room temperature in continental US; may vary elsewhere. |
||||||||||||
Storage |
-20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
||||||||||||
Solvent & Solubility |
In Vitro:
DMSO : 125 mg/mL (160.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO
+
%
+
%
Tween-80
+
%
Saline
The co-solvents required include: DMSO,
. All of co-solvents are available by MedChemExpress (MCE).
, Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration:
mg/mL
Method for preparing stock solution:
mg
drug dissolved in
μL
DMSO (Stock solution concentration: mg/mL).
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take
μL DMSO stock solution, add
μL .
μL , mix evenly, next add
μL Tween 80, mix evenly, then add
μL Saline.
If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
|
||||||||||||
Purity & Documentation |
Purity: ≥98.0% |
||||||||||||
References |
|
Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
---|
DMSO | 1 mM | 1.2822 mL | 6.4109 mL | 12.8218 mL | 32.0546 mL |
5 mM | 0.2564 mL | 1.2822 mL | 2.5644 mL | 6.4109 mL | |
10 mM | 0.1282 mL | 0.6411 mL | 1.2822 mL | 3.2055 mL | |
15 mM | 0.0855 mL | 0.4274 mL | 0.8548 mL | 2.1370 mL | |
20 mM | 0.0641 mL | 0.3205 mL | 0.6411 mL | 1.6027 mL | |
25 mM | 0.0513 mL | 0.2564 mL | 0.5129 mL | 1.2822 mL | |
30 mM | 0.0427 mL | 0.2137 mL | 0.4274 mL | 1.0685 mL | |
40 mM | 0.0321 mL | 0.1603 mL | 0.3205 mL | 0.8014 mL | |
50 mM | 0.0256 mL | 0.1282 mL | 0.2564 mL | 0.6411 mL | |
60 mM | 0.0214 mL | 0.1068 mL | 0.2137 mL | 0.5342 mL | |
80 mM | 0.0160 mL | 0.0801 mL | 0.1603 mL | 0.4007 mL | |
100 mM | 0.0128 mL | 0.0641 mL | 0.1282 mL | 0.3205 mL |
CY7-SE Related Classifications
- Others
- Others
- Fluorescent Dye