Cpeb1 Mouse shRNA Plasmid (Locus ID 12877)
Cat# TL500415
Size : 1kit
| Product Data | |
| Locus ID | 12877 |
|---|---|
| Synonyms | AU024112; Cpe-bp1; Cpeb; mCPEB; mCpeb-1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Format | Lentiviral plasmids |
| Components | Cpeb1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 12877). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC125476, NM_001252525, NM_001252526, NM_007755, NM_001357107, NM_007755.1, NM_007755.2, NM_007755.3, NM_007755.4, NM_007755.5, NM_001252526.1, NM_001252525.1, BC144948 |
| UniProt ID | P70166 |
| Summary | Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3' UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses. Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation. Induces the assembly of stress granules in the absence of stress (By similarity). Required for cell cycle progression, specifically for prophase entry (By similarity).[UniProtKB/Swiss-Prot Function] |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@biotrend-usa.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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