Corin Polyclonal Antibody
Cat# bs-7685R-20ul
Size : 20ul
Brand : Bioss
Corin Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-7685R |
Product Name | Corin Polyclonal Antibody |
Applications | ELISA, IF(ICC) |
Reactivity | Human, Rat, Sheep |
Predicted Reactivity | Mouse, Dog, Pig, Horse |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human Corin |
Immunogen Range | 165-245/1042 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 10699 |
Swiss Prot | Q9Y5Q5 |
Subcellular location | Secreted, Cell membrane |
Synonyms | CRN; ATC2; Lrp4; PEE5; TMPRSS10; Atrial natriuretic peptide-converting enzyme; Corin; Heart-specific serine proteinase ATC2; Pro-ANP-converting enzyme; Transmembrane protease serine 10 |
Background | Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1. |
Application Dilution | |
ELISA | 1:500-1000 |
IF(ICC) | 1:50-200 |