Centanamycin alkylates the A-T-rich minor groove of the DNA and thereby blocks DNA replication. Centanamycin potently inhibits replication of human cytomegalovirus (HCMV), mouse CMV (MCMV), and herpes simplex virus-2 (HSV-2) in vitro. Centanamycin-attenuated whole virion MCMV elicits a robust serum neutralizing antibody response and protects the mice from live-virus challenge. [[413577-16-9]]
Cat# orb1910080-1g
Size : 1g
Brand : Biorbyt
Centanamycin
Catalog Number: orb1910080
Catalog Number | orb1910080 |
---|---|
Category | Small Molecules |
Description | Centanamycin alkylates the A-T-rich minor groove of the DNA and thereby blocks DNA replication. Centanamycin potently inhibits replication of human cytomegalovirus (HCMV), mouse CMV (MCMV), and herpes simplex virus-2 (HSV-2) in vitro. Centanamycin-attenuated whole virion MCMV elicits a robust serum neutralizing antibody response and protects the mice from live-virus challenge. |
CAS Number | [413577-16-9] |
MW | 453.91806 |
SMILES | ClCCC1C2C(=CC=CC=2)C(N)=CC=1NC(=O)C3NC4C(=CC(OC)=C(OC)C=4OC)C=3 |
Formula | C24H24N3O4CL |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |