CD44 (CD 44, CDw44, ECM III, ECMRIII, Epican, Extracellular Matrix Receptor III, GP90 Lymphocyte Homing Adhesion Receptor, HCAM, HCELL, Heparan Sulfate Proteoglycan, Hermes Antigen, HUTCH1, Hyaluronate Receptor, Indian Blood Group, Inlu Related p80 Glycoprotein, lhr, Ly 24, MC56, MDU2, MDU3, MGC10468, MIC4, MUTCH1, PGP1, Phagocytic Glycoprotein 1, Phagocytic Glycoprotein I) (FITC)

Cat# C2398-01T-FITC-100ul

Size : 100ul

Brand : US Biological



C2398-01T-FITC Rabbit Anti-CD44 (CD 44, CDw44, ECM III, ECMRIII, Epican, Extracellular Matrix Receptor III, GP90 Lymphocyte Homing Adhesion Receptor, HCAM, HCELL, Heparan Sulfate Proteoglycan, Hermes Antigen, HUTCH1, Hyaluronate Receptor, Indian Blood Group, Inlu Related p80 Glycoprotein, lhr, Ly 24, MC56, MDU2, MDU3, MGC10468, MIC4, MUTCH1, PGP1, Phagocytic Glycoprotein 1, Phagocytic Glycoprotein I) (FITC)

Clone Type
Polyclonal
Host
rat
Source
mouse
Swiss Prot
P15379
Isotype
IgG2b
Grade
Affinity Purified
Applications
FLISA IHC IP
Crossreactivity
Bo Ca Eq Fe Hu Mk Mo Po
Shipping Temp
Blue Ice
Storage Temp
-20°C

CD44 is a a cell surface receptor for hyaluronic acid, although it can also interact with other ligands such as collagens and matrix metalloproteinases. It plays a role in a variety of cellular functions, such as adhesion, lymphocyte activation and lymph node homing. It is also involved in cell migration and plays a role in tumor metastasis. The protein has many distinct isoforms responsible for its functional diversity. ||Applications:|Suitable for use in FLISA, Flow Cytometry (Not Tested), Immunohistochemistry and Immunoprecipitation. Other applications not tested.||Recommended Dilutions:|Flow Cytometry (Not Tested): 10ul labels 10e6 cells in 100ul|Immunohistochemistry: Frozen and paraffin sections|Optimal dilutions to be determined by the researcher. ||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. |Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG2b|Clone No: IM7|Host: rat|Source: mouse|Concentration: As Reported|Form: Supplied as a liquid in PBS, pH 7.2. Labeled with Fluorescein isothiocyanate (FITC).|Purity: Purified by affinity chromatography|Immunogen: Dexamethasone-induced myeloid leukemia M1 cells.|Specificity: Recognizes mouse CD44. Species Crossreactivity: Human, Baboon, Cynomolgus monkey, Rhesus Monkey, equine, Bovine, Porcine, canine and feline||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Dexamethasone-induced myeloid leukemia M1 cells.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Fluorescein isothiocyanate (FITC).
Purity
Purified by affinity chromatography
Specificity
Recognizes mouse CD44. Species Crossreactivity: Human, Baboon, Cynomolgus monkey, Rhesus Monkey, equine, Bovine, Porcine, canine and feline
References
1. McKallip, R. J. et al. (2002) Role of CD44 in activation-induced cell death: CD44-deficient mice exhibit enhanced T cell response to conventional and superantigens. Int. Immunol. 14: 1015-1026.