Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CCR5-hIgGFc transfected HEK293 cell lysates with CCR5 monoclonal antibody, clone 6G11D1 (Cat # MAB17960).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CCR5 monoclonal antibody, clone 6G11D1 (Cat # MAB17960).
Flow Cytometry
Flow cytometric analysis of K562 cells with CCR5 monoclonal antibody, clone 6G11D1 (Cat # MAB17960) (Green). Red: Negative Control.
- Specifications
Product Description
Mouse monoclonal antibody raised against recombinant human CCR5.
Immunogen
Recombinant protein corresponding to human CCR5.
Host
Mouse
Theoretical MW (kDa)
40.5
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CCR5-hIgGFc transfected HEK293 cell lysates with CCR5 monoclonal antibody, clone 6G11D1 (Cat # MAB17960).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CCR5 monoclonal antibody, clone 6G11D1 (Cat # MAB17960).Flow Cytometry
Flow cytometric analysis of K562 cells with CCR5 monoclonal antibody, clone 6G11D1 (Cat # MAB17960) (Green). Red: Negative Control. - Gene Info — CCR5
Entrez GeneID
1234Protein Accession#
P51681Gene Name
CCR5
Gene Alias
CC-CKR-5, CCCKR5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Gene Description
chemokine (C-C motif) receptor 5
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
C-C chemokine receptor 5|C-C chemokine receptor type 5|CCR5 chemokine receptor|chemokine (C-C) receptor 5|chemokine receptor CCR5|chemr13
- Interactomes
- Pathways
- Diseases