Images
Flow Cytometry
Application

Flow Cytometry

Flow cytometric analysis of C6 cells cell only only negative control (blue) or treated with imatinib (red) or with pervanadate (green) using Phospho-c-Cbl (Tyr700) PE-conjugated antibody CblY700-E1.

View product citations for antibody RAB03032 on CiteAb
  • Specifications

    Product Description

    Rabbit recombinant monoclonal antibody raised against human CBL.Recombinant Antibody,Recombinant Antibodies,Recombinant Monoclonal Antibody,RecomAb,Recombinant Ab,Recombinant Monoclonal Antibodies,Recombinant Abs,RAB,MAB,Recombinant Mab,MAB,monoclonal Ab,monoclonal antibody

    Antibody Species

    Rabbit

    Immunogen

    A synthetic phospho-peptide corresponding to residues surrounding Tyr700 of human phospho c-Cbl

    Reactivity

    Human

    Form

    Liquid

    Conjugation

    PE

    Purification

    Protein A purification, Protein G purification

    Isotype

    IgG

    Recommend Usage

    Flow Cytometry
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    1X PBS, 0.09% Sodium azide, 0.2% BSA

    Storage Instruction

    Store at 4°C. Do not freeze.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Flow Cytometry

    Flow cytometric analysis of C6 cells cell only only negative control (blue) or treated with imatinib (red) or with pervanadate (green) using Phospho-c-Cbl (Tyr700) PE-conjugated antibody CblY700-E1.
  • Gene Info — CBL

    Entrez GeneID

    867

    Protein Accession#

    P22681

    Gene Name

    CBL

    Gene Alias

    C-CBL, CBL2, RNF55

    Gene Description

    Cas-Br-M (murine) ecotropic retroviral transforming sequence

    Omim ID

    165360

    Gene Ontology

    Hyperlink

    Gene Summary

    The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq

    Other Designations

    oncogene CBL2

  • Interactomes
  • Pathways
  • Diseases