Caspase 3 Polyclonal Antibody
Cat# bs-0081R-20ul
Size : 20ul
Brand : Bioss
Caspase 3 Polyclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bs-0081R |
Product Name | Caspase 3 Polyclonal Antibody |
Applications | WB, ELISA, IHC-P, IF(IHC-P), IF(ICC) |
Reactivity | Human, Mouse, Rat, Bovine, Pig, Chicken, Sheep, Rabbit, Others, Monkey |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human Caspase 3(Active) |
Immunogen Range | 1-100/277 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 836 |
Swiss Prot | P42574 |
Subcellular location | Cytoplasm |
Synonyms | CPP32; SCA-1; CPP32B; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; CASP3 |
Background | Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. |
Application Dilution | |
WB | 1:300-5000 |
ELISA | 1:500-1000 |
IHC-P | 1:200-400 |
IF(IHC-P) | 1:50-200 |
IF(ICC) | 1:50-200 |