P020-10MG BRL-50481, 10 mg In Stock
P020-50MG BRL-50481, 50 mg In Stock
  • Features Potent Inhibitor of PDE7
  • Induces apoptosis
  • Cell permeable
  • Room temperature storage

BRL-50481 is a potent and selective inhibitor of phosphodiesterase-7 (PDE7), Ki=180 nM. Induces apoptosis in chronic lymphocytic leukemia cells which express PDE7B. Increases mineralization in osteoblasts differentiated from hMSC. Cell permeable.