BMI1 Human shRNA Plasmid Kit (Locus ID 648)

Cat# TR314462

Size : 1kit


BMI1 Human shRNA Plasmid Kit (Locus ID 648)

SKU
TR314462
BMI1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
In Stock*
Specifications
Product Data
Locus ID 648
Synonyms flvi-2/bmi-1; FLVI2/BMI1; PCGF4; RNF51
Vector pRS
E. coli Selection Ampicillin
Format Retroviral plasmids
Components BMI1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 648). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_005180, NM_005180.1, NM_005180.2, NM_005180.3, NM_005180.4, NM_005180.5, NM_005180.6, NM_005180.7, NM_005180.8, BC011652, BC011652.2, NM_005180.9
UniProt ID P35226
Summary This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015]
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@biotrend-usa.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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