Anti-TLE1, ID (TLE1, Transducin-like enhancer protein 1, E(Sp1) homolog, Enhancer of split groucho-like protein 1) Monoclonal Antibody

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.||Applications:|Suitable for use in Western Blot, ELISA.||Recommended Dilution:|ELISA: 1:1000|Western Blot: 1:500~8000||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.