General Info
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat/African green monkey |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-TIMP2 is suitable for use in Western Blot research applications. |
Clonality: | Monoclonal |
Clone ID: | S1MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | TIMP2 |
Gene ID: | 7077 |
Uniprot ID: | TIMP2_HUMAN |
Immunogen: | Recombinant protein of human TIMP2. |
Immunogen Sequence: | VSLDVGGKKEYLIAGKAEGD GKMHITLCDFIVPWDTLSTT QKKSLNHRYQMGCECKITRC PMIPCYISSPDECLWMDWVT EKNINGHQAKFFACIKRSDG S |
Description
Post Translational Modifications | The activity of TIMP2 is dependent on the presence of disulfide bonds. |
Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. |
Protein Name | Metalloproteinase Inhibitor 2Csc-21kTissue Inhibitor Of Metalloproteinases 2Timp-2 |
Database Links | Reactome: R-HSA-1592389Reactome: R-HSA-6798695 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Metalloproteinase Inhibitor 2 antibodyAnti-Csc-21k antibodyAnti-Tissue Inhibitor Of Metalloproteinases 2 antibodyAnti-Timp-2 antibodyAnti-TIMP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance