General Info
| Host: | Rabbit |
| Applications: | ELISA/WB |
| Reactivity: | C.elegans/Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-SYDE1 (680-735) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Purification: | Affinity Purified |
| Concentration: | 0.67-0.68 µg/µl |
| Dilution Range: | WB: 1:500ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:150 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
| Gene Symbol: | SYDE1 |
| Gene ID: | 85360 |
| Uniprot ID: | SYDE1_HUMAN |
| Immunogen Region: | 680-735 |
| Immunogen: | Synthetic peptide taken within amino acid region 680-735 on human SYDE1 protein. |
Description
| Tissue Specificity | Expressed in trophoblast cells of placental villi. |
| Post Translational Modifications | Palmitoylated. Probably palmitoylated by ZDHHC3 and ZDHHC7. |
| Function | GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1. |
| Protein Name | Rho Gtpase-Activating Protein Syde1Synapse Defective Protein 1 Homolog 1Protein Syd-1 Homolog 1 |
| Database Links | Reactome: R-HSA-9013148Reactome: R-HSA-9013404Reactome: R-HSA-9013406Reactome: R-HSA-9013409Reactome: R-HSA-9013423Reactome: R-HSA-9035034 |
| Alternative Antibody Names | Anti-Rho Gtpase-Activating Protein Syde1 antibodyAnti-Synapse Defective Protein 1 Homolog 1 antibodyAnti-Protein Syd-1 Homolog 1 antibodyAnti-SYDE1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance