General Info
Host: | Rabbit |
Applications: | ELISA/IP/WB |
Reactivity: | Chimpanzee/Human/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-SLC2A5 is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | FITC |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.7 µg/µl |
Dilution Range: | WB: 1:1, 000 DB: 1:4, 000 ELISA: 1:4, 000 IP: 1:200 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
Gene Symbol: | SLC2A5 |
Gene ID: | 6518 |
Uniprot ID: | GTR5_HUMAN |
Immunogen: | Synthetic peptide corresponding to unique amino acid sequence on human GLUT 5 protein. |
Description
Tissue Specificity | Detected in skeletal muscle, and in jejunum brush border membrane and basolateral membrane (at protein level). Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue. |
Function | Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of 2-deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake. |
Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 5 Fructose Transporter Glucose Transporter Type 5 - Small Intestine Glut-5 |
Database Links | Reactome: R-HSA-6798695 Reactome: R-HSA-8981373 |
Cellular Localisation | Apical Cell Membrane Multi-Pass Membrane Protein Cell Membrane Sarcolemma Localized On The Apical Membrane Of Jejunum Villi But Also On Lateral Plasma Membranes Of The Villi Transport To The Cell Membrane Is Dependent On Rab11a |
Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 5 antibody Anti-Fructose Transporter antibody Anti-Glucose Transporter Type 5 - Small Intestine antibody Anti-Glut-5 antibody Anti-SLC2A5 antibody Anti-GLUT5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance