General Info
Host: | Rabbit |
Applications: | ELISA/IP/WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-RNase H1 (1-75) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.5-1.5 Mu g/Mu l |
Dilution Range: | WB: 1:500ELISA: 1:10, 000IP: 1:200 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
Gene Symbol: | RNASEH1 |
Gene ID: | 246243 |
Uniprot ID: | RNH1_HUMAN |
Immunogen Region: | 1-75 |
Immunogen: | Synthetic peptide corresponding to amino acids within region 1-75 on human Rnase H1 protein. |
Description
Function | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II. |
Protein Name | Ribonuclease H1Rnase H1Ribonuclease H Type Ii |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Ribonuclease H1 antibodyAnti-Rnase H1 antibodyAnti-Ribonuclease H Type Ii antibodyAnti-RNASEH1 antibodyAnti-RNH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance