General Info
| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-Immunoglobulin G is suitable for use in Immunohistochemistry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | RWP49 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Tissue culture supernatant with sodium azide |
| Concentration: | >=59 mg/L |
| Dilution Range: | IHC-P 1:200 |
| Storage Instruction: | Store at 2-8°C upon receipt. |
Information
| Immunogen: | Prokaryotic recombinant protein corresponding to 327 amino acids of the human IgG molecule. |
Description
| Background | The human immunoglobulins consist of two identical heavy chains (~50 kD) and two identical light chains, which are linked together by disulphide bonds. The light chains can be either kappa or lambda. The five immunoglobulins IgA, IgD, IgE, IgG and IgM differ in their heavy chains, and IgA and IgM differ as they can occur in polymeric forms. The heavy chain of IgG is named the gamma-chain. In humans, IgG consists of four sub classes that differ only marginally in their amino acid composition. Antibodies to IgG have been reported to be useful in the identification of plasma cells, lymphoid cells containing IgG and classifying B cell derived neoplasms. The normal B cell population is polyclonal, expressing a range of different immunoglobulins. In contrast, the majority of B cell neoplasms are characterized by the proliferation of monoclonal cells expressing one type of light chain, whereas more than one type of heavy chain can be expressed by the same cell. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance