General Info
Host: | Rabbit |
Applications: | CM/ELISA/IF/IHC/IP/WB |
Reactivity: | Human/Monkey/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-BEST1 (Mid-region) is suitable for use in Confocal Microscopy, ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | FITC |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.65 µg/µl |
Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:100ICC: 1:100IF: 1:100CFM: 1:100 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
Gene Symbol: | BEST1 |
Gene ID: | 7439 |
Uniprot ID: | BEST1_HUMAN |
Immunogen Region: | Mid-region |
Immunogen: | Mid-Region Synthetic peptide corresponding to unique amino acid sequences on human Bestrophin 1 protein. |
Description
Tissue Specificity | Predominantly expressed in the basolateral membrane of the retinal pigment epithelium. |
Post Translational Modifications | Phosphorylated by PP2A. |
Function | Forms calcium-sensitive chloride channels. Highly permeable to bicarbonate. |
Protein Name | Bestrophin-1Tu15bVitelliform Macular Dystrophy Protein 2 |
Database Links | Reactome: R-HSA-2672351 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell Membrane |
Alternative Antibody Names | Anti-Bestrophin-1 antibodyAnti-Tu15b antibodyAnti-Vitelliform Macular Dystrophy Protein 2 antibodyAnti-BEST1 antibodyAnti-VMD2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance