Synthetic peptide chosen from human Abeta (1-42) protein. Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A
Host:
Rabbit
Clonality:
Polyclonal
Purity:
Serum
Format:
Lyophilized
Quantity:
100 µl
Reconstitution:
For reconstitution add 100 µl of sterile water
Storage:
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Tested applications:
Dot Blot (Dot), ELISA (ELISA), Western blot (WB)
Recommended dilution:
1 : 1000 (Dot), 1 : 3000 (ELISA), 1 : 1000 (WB)
Expected | apparent MW:
4.5 kDa
Reactivity
Confirmed reactivity:
Human
Predicted reactivity:
Bovine, Chicken, Dog, Porcine, Rabbit
Not reactive in:
No confirmed exceptions from predicted reactivity are currently known
Application Examples
Dot blot and Western analysis • Membrane: Nitrocellulose • Blocking buffer: 5% dry milk in PBS, 0.15% Tween 20 • Antibody dilution : 1:1000 • Secondary antibody: anti-rabbit (HRP) • Detection: Enhanced Chemoluminescence (pico) 10s
Additional Information
Additional information (application):
The antibody can detect Abeta(1-42), Abeta(1-28) Abeta(1-20) and Abeta(1-17)
Background
Background:
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067
We use cookies to improve our website and to provide you with a better experience. By continuing to use the website, you agree to this. Read more.
Cookie Settings
We use cookies to personalize content and ads, to provide social media features, and to analyze our traffic. We also share information about your use of our site with our social media, advertising, and analytics partners who may combine it with other information that you've provided to them or that they've collected from your use of their services.
We respect your privacy, and that's why we give you control over which types of cookies we use on our site. You can choose to accept or decline certain types of cookies by clicking the settings button below.
Necessary Cookies
These cookies are necessary for the website to function and cannot be switched off in our systems. They are usually only set in response to actions made by you which amount to a request for services, such as setting your privacy preferences, logging in, or filling in forms. You can set your browser to block or alert you about these cookies, but some parts of the site will not then work. These cookies do not store any personally identifiable information.
Performance Cookies
These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. They help us to know which pages are the most and least popular and see how visitors move around the site. All information these cookies collect is aggregated and therefore anonymous. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance.
Functional Cookies
These cookies enable the website to provide enhanced functionality and personalization. They may be set by us or by third party providers whose services we have added to our pages. If you do not allow these cookies then some or all of these services may not function properly.
Targeting Cookies
These cookies may be set through our site by our advertising partners. They may be used by those companies to build a profile of your interests and show you relevant adverts on other sites. They do not store directly personal information, but are based on uniquely identifying your browser and internet device. If you do not allow these cookies, you will experience less targeted advertising.
By clicking “Accept All Cookies”, you agree to the use of all of the above cookies. You can change your cookie settings at any time by clicking on “Cookie Settings” and selecting the categories that you want to enable or disable.
