Acetylcysteine [616-91-1]
Cat# HY-B0215-5g
Size : 5g
Brand : MedChemExpress
Acétylcystéine (N-acétyl-L-cystéine) est un agent mucolytique qui réduit l'épaisseur du mucus. Acétylcystéine est un inhibiteur des ROS. Acétylcystéine est un précurseur de la cystéine, prévient la ferroptose induite par l'hémine en neutralisant les lipides toxiques générés par l'activité dépendante de l'arachidonate des 5-lipoxygénases. Acétylcystéine induit l'apoptose cellulaire.
Acetylcystein ist ein mucolytic agent, das die Dicke des Schleims reduziert. Acetylcystein ist ein ROS-Inhibitor. Acetylcystein ist ein Cysteinvorläufer, der die durch Hämin induzierte ferroptosis verhindert, indem er toxische Lipide neutralisiert, die durch die Arachidonat-abhängige Aktivität von 5-Lipoxygenasen erzeugt werden. Acetylcystein induziert die apoptosis.
Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities.
For research use only. We do not sell to patients.
Acetylcysteine Chemical Structure
CAS No. : 616-91-1
This product is a controlled substance and not for sale in your territory.
Based on 373 publication(s) in Google Scholar
Other Forms of Acetylcysteine:
- Acetylcysteine-d3 Get quote
- Acetylcysteine-15N Get quote
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Acetylcysteine purchased from MedChemExpress. Usage Cited in: Cell Death Discov. 2018 Apr 27;4:47. [Abstract]
- Wild-type, Prx1KO, and Prx1OE cells are each divided into three groups, which are control groups, groups treated with 100 ng/mL LPS, and groups treated with 100 ng/mL LPS and NAC. Western blot analysis is then performed with antibodies against Bax, Bcl-2, Cyto-c, caspase 3, and GAPDH, and band intensity is measured with densitometry.
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Acetylcysteine purchased from MedChemExpress. Usage Cited in: Fundam Clin Pharmacol. 2017 Feb;31(1):64-74. [Abstract]
- Advanced oxidation production product (AOPP)-triggered apoptosis-related signals are triggered by ROS production. Human chondrocytes are pretreated with N-Acetylcysteine (NAC; 5 mM) for 60 min, and then, chondrocyte are co-incubated with AOPP and NAC for 24 h. (a) Pretreatment of ROS scavenger NAC markedly alleviates AOPP-triggered mitochondria-mediated apoptosis proteins. (b) Pretreatment of chondrocyte with NAC abrogates the intracellular Ca2+ mobilization. (c) NAC pretreatment atte
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Acetylcysteine purchased from MedChemExpress. Usage Cited in: Sci Rep. 2016 Oct 27;6:35995. [Abstract]
- Pretreatment of NAC, a free radical scavenger, largely decreases the expression of caspase-3 and almost abolishes the H2O2 induced upregulation of PRX1. Western blot analysis shows the pretreatment of osteoblast cells with E2 partially abrogates the increased PRX1 and caspase-3 expressions induced by H2O2.