NDRG1 (phospho T346) monoclonal antibody, clone F5 (APC)
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- Specifications
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human NDRG1.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding T346 of human NDRG1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Conjugation
APC
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Flow Cytometry
Flow cytometric analysis of THP-1 cells with NDRG1 (phospho T346) monoclonal antibody, clone F5 (APC) (Cat # MAB23440). Unstained and untreated as negative control (blue) or stained and untreated (red) or stained and treated with IFNa plus IL-4 and pervanadate (green). - Gene Info — NDRG1
Entrez GeneID
10397Gene Name
NDRG1
Gene Alias
CAP43, CMT4D, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5
Gene Description
N-myc downstream regulated 1
Gene Ontology
HyperlinkGene Summary
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. It is necessary for p53-mediated caspase activation and apoptosis. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
differentiation-related gene 1 protein|nickel-specific induction protein Cap43|protein regulated by oxygen-1|reducing agents and tunicamycin-responsive protein|tunicamycin-responsive protein
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- Diseases