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| 25 mg | $115.00 |
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BAPTA-AM [126150-97-8]
Cat# 10-1203-5mg
Size : 5mg
Brand : Focus Biomolecules
BAPTA-AM | Cellular calcium sponge
CAS:
126150-97-8
Catalog Number:
10-1203
Activity:
cellular calcium sponge
Chemical Name:
1,2-bis-(2-Aminophenoxy)ethane-N,N,N’,N’-tetraacetic acid, tetraacetoxymethyl ester
Molecular Weight:
764.7
Molecular Formula:
C34H40N2O18
Solubility:
Soluble in DMSO (up to 15 mg/ml), in DMF (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
95% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF or ethanol may be stored at -20°C for up to 1 week.
Shipping Code:
RT
BAPTA-AM (126150-97-8) is a selective cell permeable Ca2+ chelator. It is a widely used intracellular calcium sponge.1,2 Rapidly taken up by cells where it is irreversibly hydrolyzed to BAPTA by intracellular esterases. Pretreatment of cells with BAPTA-AM inhibits thapsigargin-induced responses.3
References/Citations:
1) Smith et al. (1992), Cytosolic calcium as a second messenger for collagen-induced platelet responses; Biochem. J., 288 925
2) Yoshida et al. (1993), Role of calcium ion in induction of apoptosis by etoposide in human leukemia HL-60 cells; Biochem. Biophys. Res. Commun., 196 927
3) Jiang et al. (1994), Intracellular Ca2+ signals activate apoptosis in thymocytes: studies using the Ca(2+)-ATPase inhibitor thapsigargin; Exp. Cell Res., 212 84
CAS:
126150-97-8
Catalog Number:
10-1203
Activity:
cellular calcium sponge
Chemical Name:
1,2-bis-(2-Aminophenoxy)ethane-N,N,N’,N’-tetraacetic acid, tetraacetoxymethyl ester
Molecular Weight:
764.7
Molecular Formula:
C34H40N2O18
Solubility:
Soluble in DMSO (up to 15 mg/ml), in DMF (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
95% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF or ethanol may be stored at -20°C for up to 1 week.
Shipping Code:
RT
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a restocking/refund fee
BAPTA-AM (126150-97-8) is a selective cell permeable Ca2+ chelator. It is a widely used intracellular calcium sponge.1,2 Rapidly taken up by cells where it is irreversibly hydrolyzed to BAPTA by intracellular esterases. Pretreatment of cells with BAPTA-AM inhibits thapsigargin-induced responses.3
References/Citations:
1) Smith et al. (1992), Cytosolic calcium as a second messenger for collagen-induced platelet responses; Biochem. J., 288 925
2) Yoshida et al. (1993), Role of calcium ion in induction of apoptosis by etoposide in human leukemia HL-60 cells; Biochem. Biophys. Res. Commun., 196 927
3) Jiang et al. (1994), Intracellular Ca2+ signals activate apoptosis in thymocytes: studies using the Ca(2+)-ATPase inhibitor thapsigargin; Exp. Cell Res., 212 84
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