General Info
| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-L-selectin is suitable for use in Flow Cytometry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | DREG56 |
| Conjugation: | AF647 |
| Isotype: | IgG1k |
| Formulation: | PBS with 0.05% Proclin300, 1% BSA |
| Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Information
| Gene Symbol: | SELL |
| Gene ID: | 6402 |
| Uniprot ID: | LYAM1_HUMAN |
Description
| Tissue Specificity | Expressed in B-cell lines and T-lymphocytes. |
| Post Translational Modifications | N-glycosylated. |
| Function | Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. |
| Protein Name | L-SelectinCd62 Antigen-Like Family Member LLeukocyte Adhesion Molecule 1Lam-1Leukocyte Surface Antigen Leu-8Leukocyte-Endothelial Cell Adhesion Molecule 1Lecam1Lymph Node Homing ReceptorTq1Gp90-MelCd Antigen Cd62l |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-L-Selectin antibodyAnti-Cd62 Antigen-Like Family Member L antibodyAnti-Leukocyte Adhesion Molecule 1 antibodyAnti-Lam-1 antibodyAnti-Leukocyte Surface Antigen Leu-8 antibodyAnti-Leukocyte-Endothelial Cell Adhesion Molecule 1 antibodyAnti-Lecam1 antibodyAnti-Lymph Node Homing Receptor antibodyAnti-Tq1 antibodyAnti-Gp90-Mel antibodyAnti-Cd Antigen Cd62l antibodyAnti-SELL antibodyAnti-LNHR antibodyAnti-LYAM1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance