ALK Gene Fusion Detection BioGenomics™ FISH Kit

Sample Type: |Paraffin-embedded non-small cell lung cancer tissue sections.||Intended Use:|FISH||Background:|FISH is the first and only diagnostic test approved for the identification of ALK gene status in patients with non-small cell lung cancer. ALK gene recombination is a unique biological tumor characteristic of non-small cell lung cancer. Frame recombination leads to ALK kinase domain close to the promoter of another gene, resulting in the formation of a new gene fusion associated to the cancer development. ALK gene can fuse with several different genes such as EML4, TFG and KIF5B.||Application: |All ALK genes recombination detection by fluorescence in situ hybridization (FISH).||Features and Advantages:|1. First ready-to-use ALK gene recombination assay kit.|2. All ALK rearrangements can be identified, including the fusion of EML4, TFG and KIF5B and other genes.|3. Low negative results and reliable results determination.||Probe Name:|ALK||Fluorophore:|Orange/Green||Storage and Stability:|Store powder at 4°C liquid at -20°C. Store other components at 4°C. Stable for 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.