Rat anti-mouse CD45R/PE-Cy7 monoclonal antibody
Cat# bsm-30307A-PE-CY7-100T
Size : 100T
Brand : Bioss
mouse CD45R/PE-Cy7
Applications
Reactivity
| Overview | |
| Catalog # | bsm-30307a-pe-cy7-100t |
| Product Name | mouse CD45R/PE-Cy7 |
| Applications | FCM |
| Reactivity | Mouse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rat |
| Clonality | Monoclonal |
| Clone # | 3B6 |
| Isotype | IgG2a/Kappa |
| Concentration | n/a |
| Purification | Affinity purified by Protein G |
| Storage Buffer | 0.01M PBS, 0.5%BSA, 0.02% Proclin300 |
| Storage Condition | Store at 2-8°C |
| Target | |
| Gene ID | 19264.0 |
| Swiss Prot | P06800 |
| Background | CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. |
| Application Dilution | |
| FCM | 10ul/10^6 cells in 100ul |